Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615968 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDSMN1; SMN2TDP1 | |
| SCHEMBL25178599 | 0.88 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDSMN1; SMN2TDP1 | |
| SCHEMBL11566331 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDSMN1; SMN2TDP1 | |
| SCHEMBL11568854 | 0.85 | CTSS (0.45) | ALDH1A1MAPTHPGDSMN1; SMN2TDP1 | |
| SCHEMBL1285759 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDSMN1; SMN2TDP1 | |
| SCHEMBL23944461 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDSMN1; SMN2TDP1 | |
| SCHEMBL25901621 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDSMN1; SMN2TDP1 | |
| SCHEMBL11568741 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDSMN1; SMN2TDP1 | |
| Dimethylformamide SCHEMBL11567929 | 0.79 | CTSS (0.41) | ALDH1A1MAPTHPGDSMN1; SMN2ABCB1 | |
| SCHEMBL22326382 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767254-A | INCORPORATING IMINO-BOUND MOIETY | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 1998-06-16 | — | — | US | disclosed |
| US-5470949-A | Method for making amino acid glycosides and glycopeptides | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 1995-11-28 | — | — | US | disclosed |