Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638125 | 0.96 | TSHR (0.38) | TSHRCES1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL11792366 | 0.88 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL7066435 | 0.85 | CES1 (0.47) | TSHRCES1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL7179939 | 0.85 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL6759981 | 0.83 | CES1 (0.46) | TSHRCES1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL6887437 | 0.83 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL3117799 | 0.81 | TSHR (0.34) | TSHRCES1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL9637020 | 0.80 | TSHR (0.56) | TSHRCES1ALDH1A1 | |
| SCHEMBL27679774 | 0.79 | CES1 (0.35) | CES1 | |
| SCHEMBL30366247 | 0.77 | TSHR (0.57) | TSHRCES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822238-B2 | Compositions comprising tetrahydrofurfuryl and alkoxylated alkyl esters as plasticisers for biodegradable resins | PROVIRON HOLDING N.V. (BE) | 2017-11-21 | — | — | US | claimed |
| US-20160319101-A1 | COMPOSITIONS COMPRISING TETRAHYDROFURFURYL AND ALKOXYLATED ALKYL ESTERS AS PLASTICISERS FOR BIODEGRADABLE RESINS | PROVIRON HOLDING N.V. (BE) | 2016-11-03 | — | — | US | claimed |
| EP-3083806-A1 | COMPOSITIONS COMPRISING TETRAHYDROFURFURYL AND ALKOXYLATED ALKYL ESTERS AS PLASTICISERS FOR BIODEGRADABLE RESINS | Proviron Holding N.V. (BE) | 2016-10-26 | — | — | EP | claimed |
| WO-2015090620-A1 | COMPOSITIONS COMPRISING TETRAHYDROFURFURYL AND ALKOXYLATED ALKYL ESTERS AS PLASTICISERS FOR BIODEGRADABLE RESINS | PROVIRON HOLDING N.V. (BE) | 2015-06-25 | — | — | WO | claimed |
| EP-0525880-B1 | Catalytic alkylation process | FMC CORP (US) | 1998-05-06 | — | — | EP | claimed |
| US-5332853-A | Alkylating tetrachlorosilane or an alkylchlorosilane with an alkyllithium using ether, metal alkoxide, amine, or metal amide as catalyst | FMC CORPORATION (US) | 1994-07-26 | — | — | US | claimed |
| US-9822238-B2 | Compositions comprising tetrahydrofurfuryl and alkoxylated alkyl esters as plasticisers for biodegradable resins | PROVIRON HOLDING N.V. (BE) | 2017-11-21 | — | — | US | disclosed |
| US-20160319101-A1 | COMPOSITIONS COMPRISING TETRAHYDROFURFURYL AND ALKOXYLATED ALKYL ESTERS AS PLASTICISERS FOR BIODEGRADABLE RESINS | PROVIRON HOLDING N.V. (BE) | 2016-11-03 | — | — | US | disclosed |
| EP-3083806-A1 | COMPOSITIONS COMPRISING TETRAHYDROFURFURYL AND ALKOXYLATED ALKYL ESTERS AS PLASTICISERS FOR BIODEGRADABLE RESINS | Proviron Holding N.V. (BE) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015090620-A1 | COMPOSITIONS COMPRISING TETRAHYDROFURFURYL AND ALKOXYLATED ALKYL ESTERS AS PLASTICISERS FOR BIODEGRADABLE RESINS | PROVIRON HOLDING N.V. (BE) | 2015-06-25 | — | — | WO | disclosed |
| EP-0525880-B1 | Catalytic alkylation process | FMC CORP (US) | 1998-05-06 | — | — | EP | disclosed |
| US-4061612-A | Low temperature plasticizers for specialty rubbers consisting of diesters of dicarboxylic acids with hexyloxyethoxyethanol or butoxyethoxyethoxyethanol | THIOKOL CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |
| US-4061612-A | Low temperature plasticizers for specialty rubbers consisting of diesters of dicarboxylic acids with hexyloxyethoxyethanol or butoxyethoxyethoxyethanol | THIOKOL CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |
| US-4061612-A | Low temperature plasticizers for specialty rubbers consisting of diesters of dicarboxylic acids with hexyloxyethoxyethanol or butoxyethoxyethoxyethanol | THIOKOL CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |
| US-3951977-A | MINERAL OIL SOLUBLE, ANTIWEAR, ANTIRUST, DISPERSION DETERGENT ADDITIVES | STANDARD OIL COMPANY (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160319101-A1 | COMPOSITIONS COMPRISING TETRAHYDROFURFURYL AND ALKOXYLATED ALKYL ESTERS AS PLASTICISERS FOR BIODEGRADABLE RESINS | ALKBH3, FTO, ALKBH5 | TSHR 4443/4885CES1 1087/4885ALDH1A1 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.