Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545735 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SIGMAR1MAPTHPGDEPHX2 | |
| SCHEMBL9248089 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SIGMAR1MAPTHPGDEPHX2 | |
| SCHEMBL9384729 | 0.83 | SIGMAR1 (0.39) | ALDH1A1SIGMAR1MAPTKMT2ANPC1L1 | |
| SCHEMBL9170189 | 0.83 | SIGMAR1 (0.39) | ALDH1A1SIGMAR1MAPTKMT2ANPC1L1 | |
| SCHEMBL9170182 | 0.83 | SIGMAR1 (0.39) | ALDH1A1SIGMAR1MAPTKMT2ANPC1L1 | |
| SCHEMBL9545728 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDKMT2AHTT | |
| SCHEMBL8616156 | 0.81 | SIGMAR1 (0.51) | ALDH1A1SIGMAR1MAPTEPHX2KMT2A | |
| SCHEMBL8615813 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SIGMAR1MAPTHPGDEPHX2 | |
| SCHEMBL8617737 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SIGMAR1MAPTHPGDEPHX2 | |
| SCHEMBL8619315 | 0.74 | SIGMAR1 (0.40) | ALDH1A1SIGMAR1MAPTKMT2ANPC1L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716948-A | 3-substituted carbacephems | PFIZER INC. (US) | 1998-02-10 | — | — | US | disclosed |
| WO-1993025551-A1 | 3-SUBSTITUTED CARBACEPHEMS | SMITHKLINE BEECHAM PLC (GB) | 1993-12-23 | — | — | WO | disclosed |