SCHEMBL8616174

SCHEMBL8616174

COC(=O)c1ccccc1OC(=O)NC1C(=O)N(CCC(C)C)c2cc(Cl)c(Cl)cc2N(c2ccccc2)C1=O

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 13/20 0.66
XIAP P98170 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8616173 0.86 CCKBR (0.63) CCKBR
SCHEMBL8639233 0.79 CCKBR (1.00) CCKBR
SCHEMBL8617280 0.77 CCKBR (0.67) CCKBR
SCHEMBL8620789 0.76 CCKBR (0.56) CCKBR
SCHEMBL8617148 0.76 CCKBR (0.68) CCKBR
SCHEMBL8623451 0.73 CCKBR (0.64) CCKBR
SCHEMBL8615675 0.73 CCKBR (0.74) CCKBR
SCHEMBL8622431 0.72 CCKBR (0.77) CCKBR
SCHEMBL8638925 0.71 CCKBR (1.00) CCKBR
SCHEMBL8634816 0.71 CCKBR (1.00) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623118-B1 CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE GLAXO WELLCOME SPA (IT) 1998-05-13 EP disclosed