Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20511474 | 1.00 | ESR1 (0.34) | ESR1ESR2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9406356 | 0.93 | ESR1 (0.31) | ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL9406344 | 0.93 | ESR1 (0.31) | ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL9406353 | 0.93 | ESR1 (0.31) | ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL17252249 | 0.86 | JAK2 (0.31) | — | |
| SCHEMBL17253449 | 0.86 | JAK2 (0.31) | — | |
| SCHEMBL10107071 | 0.86 | JAK2 (0.31) | — | |
| SCHEMBL131878 | 0.86 | — | — | |
| SCHEMBL25068750 | 0.85 | EPHX2 (0.35) | — | |
| SCHEMBL15577005 | 0.85 | EPHX2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018175628-A1 | BIOCATALYTIC SYNTHESIS OF STRAINED CARBOCYCLES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-09-27 | — | — | WO | disclosed |
| US-20170001990-A1 | PIPERIDINE-DIONE DERIVATIVES | GENENTECH, INC. (US) | 2017-01-05 | — | — | US | disclosed |
| WO-2015140133-A1 | PIPERIDINE-DIONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2015-09-24 | — | — | WO | disclosed |
| US-8900791-B2 | Actinic ray-sensitive or radiation-sensitive resin composition and method of forming pattern with the composition | FUJIFILM CORPORATION (JP) | 2014-12-02 | — | — | US | disclosed |
| US-8900791-B2 | Actinic ray-sensitive or radiation-sensitive resin composition and method of forming pattern with the composition | FUJIFILM CORPORATION (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20110171577-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110171577-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| WO-2010035905-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-04-01 | — | — | WO | disclosed |
| EP-1173421-B1 | INDOLE DERIVATIVES AS ANTI-INFLAMMATION AGENTS | ASTRAZENECA AB (SE) | 2007-10-03 | — | — | EP | disclosed |
| CN-1060150-C | Process | EASTMAN CHEM CO (US) | 2001-01-03 | — | — | CN | disclosed |
| US-5286725-A | Pyridazinones endowed with acaricide and insecticide action | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-02-15 | — | — | US | disclosed |
| EP-0415859-B1 | Polyesters colored with the residue of heat stable anthraquinone compounds | EASTMAN KODAK CO (US) | 1993-11-03 | — | — | EP | disclosed |
| EP-0489841-A1 | POLYESTERS COLORED WITH THE RESIDUE OF HEAT STABLE ANTHRAQUINONE COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0476573-A1 | 2-tButyl-4-chloro-5-(4-ibutylmethylcyclohexyl)-methylthio-3(H)-pyridazinone having acaricidal and insecticidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1992-03-25 | — | — | EP | disclosed |
| WO-1991003509-A1 | POLYESTERS COLORED WITH THE RESIDUE OF HEAT STABLE ANTHRAQUINONE COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1991-03-21 | — | — | WO | disclosed |
| US-4999418-A | Food Containers | EASTMAN KODAK COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| EP-0415859-A1 | Polyesters colored with the residue of heat stable anthraquinone compounds | EASTMAN CHEMICAL COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| EP-0132839-B1 | TERPENE ETHERS AND PROCESS FOR THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-04 | — | — | EP | disclosed |
| US-4590302-A | Terpene ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-20 | — | — | US | disclosed |
| EP-0132839-A1 | Terpene ethers and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001990-A1 | PIPERIDINE-DIONE DERIVATIVES | DRD4, ADORA1, ADORA3 | ESR1 512/4885ESR2 488/4885CYP3A4 122/4885 |
| US-20110171577-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION | ARSA, RAD51, ARID2 | ESR1 492/4885ESR2 178/4885CYP3A4 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.