Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617926 | 0.87 | CDK2 (0.35) | CDK2KMT2ANPC1RAB9ACA2 | |
| SCHEMBL8624748 | 0.85 | KMT2A (0.33) | CDK2KMT2ANPC1RAB9ACA2 | |
| SCHEMBL8622149 | 0.85 | KMT2A (0.35) | CDK2KMT2ANPC1RAB9ACA2 | |
| SCHEMBL8619799 | 0.84 | CDK2 (0.38) | CDK2KMT2ANPC1RAB9ACA2 | |
| SCHEMBL3680432 | 0.81 | KMT2A (0.56) | CDK2KMT2ANPC1RAB9ACA2 | |
| SCHEMBL8621405 | 0.81 | GRIA1 (0.41) | CDK2KMT2ANPC1RAB9ACA2 | |
| SCHEMBL7347926 | 0.78 | GRIN2D (0.42) | KMT2ACA2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8618907 | 0.78 | KMT2A (0.32) | CDK2KMT2ANPC1RAB9ACA2 | |
| SCHEMBL8624187 | 0.77 | PTGS2 (0.35) | KMT2ACA2KDM4EMEN1ALDH1A1 | |
| Bicarbonate SCHEMBL8805354 | 0.77 | CDK2 (0.41) | CDK2KMT2ANPC1RAB9ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |