Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037032 | 0.90 | PTGS2 (0.31) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL8624748 | 0.90 | KMT2A (0.33) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL8617926 | 0.87 | CDK2 (0.35) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL8624187 | 0.87 | PTGS2 (0.35) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL8624317 | 0.83 | KDM4E (0.51) | KMT2AKDM4EMEN1ALDH1A1CA2 | |
| SCHEMBL8624851 | 0.80 | KMT2A (0.33) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL8616696 | 0.78 | CDK2 (0.37) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL9037631 | 0.75 | KDM4E (0.42) | KMT2AKDM4EMEN1ALDH1A1CA2 | |
| SCHEMBL8619799 | 0.75 | CDK2 (0.38) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL8619987 | 0.74 | SIRT2 (0.38) | LMNATSHRCA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |