Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624187 | 0.86 | PTGS2 (0.35) | KMT2ACA2CA1CA9KDM4E | |
| SCHEMBL8616696 | 0.85 | CDK2 (0.37) | KMT2ANPC1RAB9ACDK2CA2 | |
| SCHEMBL8617926 | 0.82 | CDK2 (0.35) | KMT2ANPC1RAB9ACDK2CA2 | |
| SCHEMBL8620605 | 0.82 | KMT2A (0.53) | KMT2ANPC1RAB9ACDK2CA2 | |
| SCHEMBL8619799 | 0.79 | CDK2 (0.38) | KMT2ANPC1RAB9ACDK2CA2 | |
| SCHEMBL8621405 | 0.78 | GRIA1 (0.41) | KMT2ANPC1RAB9ACDK2CA2 | |
| SCHEMBL8624748 | 0.74 | KMT2A (0.33) | KMT2ANPC1RAB9ACDK2CA2 | |
| Bicarbonate SCHEMBL8805354 | 0.74 | CDK2 (0.41) | KMT2ANPC1RAB9ACDK2CA2 | |
| SCHEMBL8618907 | 0.74 | KMT2A (0.32) | KMT2ANPC1RAB9ACDK2CA2 | |
| SCHEMBL8619832 | 0.73 | SIRT2 (0.41) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |