Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18106575 | 0.81 | HDAC1 (0.53) | ACHESLC22A12DDB1CRBNALDH1A1 | |
| SCHEMBL16030871 | 0.81 | CYP1A2 (0.55) | ACHESLC22A12DDB1CRBNALDH1A1 | |
| SCHEMBL118883 | 0.81 | HDAC1 (0.53) | ACHESLC22A12DDB1CRBNALDH1A1 | |
| SCHEMBL2001003 | 0.81 | ACHE (0.48) | ACHESLC22A12DDB1CRBNALDH1A1 | |
| Hydrochloric Acid SCHEMBL28914132 | 0.80 | ACHE (0.47) | ACHESLC22A12DDB1CRBNALDH1A1 | |
| SCHEMBL29558 | 0.80 | ALDH1A1 (0.66) | DDB1CRBNALDH1A1MEN1USP2 | |
| SCHEMBL29875634 | 0.80 | ALDH1A1 (0.66) | DDB1CRBNALDH1A1MEN1USP2 | |
| SCHEMBL8490913 | 0.78 | ACHE (0.48) | ACHESLC22A12ALDH1A1HDAC1HDAC6 | |
| SCHEMBL6177893 | 0.78 | ACHE (0.63) | ACHESLC22A12ALDH1A1AKR1B10AKR1A1 | |
| SCHEMBL21635502 | 0.77 | HTR2C (0.42) | SLC22A12ALDH1A1MEN1USP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |