Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | CDK4 | P11802 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | CCND1 | P24385 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875634 | 1.00 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL1461825 | 0.89 | HDAC1 (0.63) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL29483474 | 0.89 | HDAC1 (0.63) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL28567500 | 0.87 | DRD4 (0.61) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL15447287 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL3850387 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL9501323 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL29571652 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL3096260 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL3098204 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115353478-A | Preparation method of indole compound | 南京工业大学 | 2022-11-18 | — | — | CN | claimed |
| CN-115197114-A | Aromatic selenium cyanogen ester compound and green synthesis method and application thereof | 南宁师范大学 | 2022-10-18 | — | — | CN | claimed |
| WO-2020046244-A2 | A NEW METHOD FOR SYNTHESIS OF C- 5 ALKYLATED INDOLINE AND INDOLE DERIVATIVES | ATATÜRK ÜNİVERSİTESİ BİLİMSEL ARAŞTIRMA PROJELERİ BİRİMİ (TR) | 2020-03-05 | — | — | WO | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| CN-115353478-B | Preparation method of indole compound | 南京工业大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-115197114-B | Aromatic selenocyanum compound and green synthesis method and application thereof | 南宁师范大学 | 2023-09-05 | — | — | CN | disclosed |
| EP-3265447-B1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | HUNTSMAN ADVANCED MAT AMERICAS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-115353478-A | Preparation method of indole compound | 南京工业大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-115197114-A | Aromatic selenium cyanogen ester compound and green synthesis method and application thereof | 南宁师范大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-112898191-B | Arylation method of indoline | 绍兴文理学院 | 2022-04-26 | — | — | CN | disclosed |
| US-20220071956-A1 | COMPOSITION FOR SUPRESSING SECRETION OF EXTRACELLULAR VESICLES | NISSAN CHEMICAL CORPORATION (JP) | 2022-03-10 | — | — | US | disclosed |
| CN-107428708-B | Benzoxazine low temperature curable compositions | 亨斯迈先进材料美国有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| US-4035391-A | Phthalide and naphthalide derivatives | POLAROID CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |
| US-4032545-A | PHTHALIDES AND NAPHTHALIDES | POLAROID CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
| US-4001278-A | INDOLE PHTHALIDES AND NAPHTHALIDES | POLAROID CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-4001275-A | INDOLE DEHYDRO PHTHALIDES AND NAPHTHALIDES | POLAROID CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3954799-A | Protonated indole phthalides and naphthalides | POLAROID CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
| US-3941807-A | Indole dehydro phthalides and naphthalides | POLAROID CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
| US-3931227-A | 3,3-Di-(indolin-5-yl)-phthalides and naphthalides | POLAROID CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931228-A | Process for preparing phthalide and naphthalide indicator dyes | POLAROID CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220071956-A1 | COMPOSITION FOR SUPRESSING SECRETION OF EXTRACELLULAR VESICLES | EXOSC9, EXOSC10, EXOSC5 | ALDH1A1 2936/4885MEN1 146/4885KMT2A 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.