Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215152 | 0.85 | TP53 (0.54) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL18103163 | 0.81 | NPC1 (0.88) | KMT2AMEN1POLBKDM4ENPC1 | |
| SCHEMBL14715847 | 0.81 | PTPN1 (0.84) | KMT2AMEN1POLBKDM4ENPC1 | |
| SCHEMBL14715824 | 0.81 | NPC1 (0.88) | KMT2AMEN1POLBKDM4ENPC1 | |
| SCHEMBL22648045 | 0.81 | NPC1 (0.56) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL26953087 | 0.79 | PTPN1 (0.88) | KMT2AMEN1POLBKDM4ENPC1 | |
| SCHEMBL1315526 | 0.79 | PTPN1 (0.87) | KMT2AMEN1POLBKDM4ENPC1 | |
| SCHEMBL126415 | 0.79 | PTPN1 (0.87) | KMT2AMEN1POLBKDM4ENPC1 | |
| SCHEMBL22648006 | 0.77 | CRHBP (0.52) | KMT2AMEN1POLBKDM4ENPC1 | |
| SCHEMBL22648796 | 0.77 | RAB9A (0.52) | KMT2AMEN1POLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611754-B1 | Dimerized thiourea derivatives, near-infrared absorbents comprising the same, and heat wave shielding materials comprising the same | JUJO PAPER CO LTD (JP) | 1998-04-22 | — | — | EP | disclosed |
| EP-0611754-A1 | Dimerized thiourea derivatives, near-infrared absorbents comprising the same, and heat wave shielding materials comprising the same | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |