Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599306 | 0.88 | MAOA (0.58) | TP53SMN1; SMN2EPHX2EPHX1TSHR | |
| SCHEMBL27568887 | 0.87 | SMN1; SMN2 (0.51) | TP53SMN1; SMN2EPHX2EPHX1TSHR | |
| SCHEMBL22648045 | 0.87 | NPC1 (0.56) | TP53SMN1; SMN2HSD17B10POLBMAPT | |
| SCHEMBL8616935 | 0.85 | KMT2A (0.61) | SMN1; SMN2POLBMAPTKMT2AMEN1 | |
| SCHEMBL22648006 | 0.82 | CRHBP (0.52) | TP53SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL22648796 | 0.82 | RAB9A (0.52) | TP53SMN1; SMN2EPHX1TSHRPOLB | |
| SCHEMBL11869490 | 0.82 | HSD17B10 (0.56) | TP53SMN1; SMN2TSHRHSD17B10NAPRT | |
| SCHEMBL12132227 | 0.79 | EPHX2 (0.61) | TP53SMN1; SMN2EPHX2EPHX1TSHR | |
| SCHEMBL3067346 | 0.79 | EPHX2 (0.61) | TP53SMN1; SMN2EPHX2EPHX1TSHR | |
| SCHEMBL11285224 | 0.79 | MAPT (0.49) | TP53SMN1; SMN2EPHX2EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046645-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2021-06-29 | — | — | US | disclosed |
| EP-3363785-B1 | ISOTHIOCYANATE PRODUCTION METHODS | ASAHI CHEMICAL IND (JP) | 2020-09-16 | — | — | EP | disclosed |
| US-20190233371-A1 | Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2019-08-01 | — | — | US | disclosed |
| EP-3214071-B1 | ISOTHIOCYANATE COMPOSITION | ASAHI CHEMICAL IND (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-10308601-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2019-06-04 | — | — | US | disclosed |
| EP-3363785-A1 | ISOTHIOCYANATE PRODUCTION METHODS | Asahi Kasei Chemicals Corporation (JP) | 2018-08-22 | — | — | EP | disclosed |
| EP-3214071-A1 | ISOTHIOCYANATE COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2017-09-06 | — | — | EP | disclosed |
| US-20160016901-A1 | ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-21 | — | — | US | disclosed |
| EP-2966060-A1 | ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2016-01-13 | — | — | EP | disclosed |
| EP-1660469-B1 | PROCESS FOR THE PREPARATION OF 11-(1-PIPERAZINYL)DIBENZO 'B, F! '1 ,4!-THIAZEPINE, AN INTERMEDIATE IN THE SYNTHESIS OF THE ANTIPSYCHOTIC DRUG QUETIAPINE | HELM AG (DE) | 2007-08-29 | — | — | EP | disclosed |
| EP-1660469-A1 | PROCESS FOR THE PREPARATION OF 11-(1-PIPERAZINYL)DIBENZO 'B, F! '1 ,4!-THIAZEPINE, AN INTERMEDIATE IN THE SYNTHESIS OF THE ANTIPSYCHOTIC DRUG QUETIAPINE | Helm AG (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005012274-A1 | PROCESS FOR THE PREPARATION OF 11-(1-PIPERAZINYL)DIBENZO `B, F! `1 ,4!-THIAZEPINE, AN INTERMEDIATE IN THE SYNTHESIS OF THE ANTIPSYCHOTIC DRUG QUETIAPINE | HELM AG (DE) | 2005-02-10 | — | — | WO | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046645-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | TST, SLCO4C1, SLCO2B1 | TP53 3955/4885SMN1; SMN2 4351/4885EPHX2 1370/4885 |
| US-20160016901-A1 | ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION | TST, SLCO4C1, SLCO2B1 | TP53 3955/4885SMN1; SMN2 4351/4885EPHX2 1370/4885 |
| US-20190233371-A1 | Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition | TST, SLCO4C1, SLCO2B1 | TP53 3955/4885SMN1; SMN2 4351/4885EPHX2 1370/4885 |
| US-10308601-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | TST, SLCO4C1, SLCO2B1 | TP53 3955/4885SMN1; SMN2 4351/4885EPHX2 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.