Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261367 | 0.83 | THRB (0.45) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL5962150 | 0.83 | ALDH1A1 (0.58) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL10594437 | 0.81 | THRB (0.44) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL5606632 | 0.80 | — | — | |
| SCHEMBL28387026 | 0.79 | THRB (0.42) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL29016951 | 0.79 | THRB (0.42) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL1791414 | 0.79 | ADRA2A (0.43) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL29173022 | 0.79 | THRB (0.68) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL631462 | 0.79 | HSD17B10 (0.37) | THRBALDH1A1TSHRHSD17B10CES2 | |
| SCHEMBL1794656 | 0.78 | TSHR (0.47) | THRBALDH1A1TSHRTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667339-B1 | Novel unsaturated peroxides, polymeric peroxides derived therefrom and their uses | ATOCHEM NORTH AMERICA ELF (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5494988-A | FREE RADICAL INITIATORS AS MONOMERS; CROSSLINKING UNSATURATED POLYESTERS; ADDITION, GRAFT AND BLOCK POLYMERIZATION; COMPATIBILIZING BLENDS | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5489699-A | USED AS FREE RADICAL GENERATOR, POLYMERIZING ETHYNICALLY UNSATURATED MONOMERS, CURING AGENT, RHEOLOGICAL MODIFIER,AND FOR GRAFTING AND COMPATIBILIZING POLYMER BLEND | ELFATOCHEM NORTH AMERICA, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5475072-A | Curing; crosslinking; modifiying; grafting; compatibilizing | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-12-12 | — | — | US | disclosed |
| EP-0667339-A1 | Novel unsaturated peroxides, polymeric derived therefrom and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-08-16 | — | — | EP | disclosed |