Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.48 |
| ▸ | MEN1 | O00255 | 10/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617827 | 0.88 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL8614773 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL8618610 | 0.84 | LMNA (0.63) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL8616980 | 0.82 | KMT2A (0.58) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL8617125 | 0.81 | TACR3 (0.42) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL8614851 | 0.80 | MEN1 (0.67) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL8618625 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL8617999 | 0.79 | DHODH (0.57) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL8614314 | 0.79 | KMT2A (0.65) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL8617116 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |