Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | HMGCR | P04035 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620210 | 0.78 | ALDH1A1 (0.36) | HMGCRPOLBTSHRCYP3A4CYP2C9 | |
| SCHEMBL1849754 | 0.75 | TSHR (0.40) | PPARDHMGCRPOLBL3MBTL1TSHR | |
| SCHEMBL9063886 | 0.74 | PPARD (0.44) | PPARDHMGCRPOLBL3MBTL1TSHR | |
| SCHEMBL9723381 | 0.74 | TSHR (0.39) | PPARDHMGCRPOLBL3MBTL1TSHR | |
| SCHEMBL9063345 | 0.71 | PPARD (0.46) | PPARDHMGCRPOLBL3MBTL1TSHR | |
| SCHEMBL27666450 | 0.69 | PPARD (0.43) | PPARDHMGCRPOLBTSHRCYP3A4 | |
| SCHEMBL9652021 | 0.69 | TSHR (0.48) | PPARDHMGCRPOLBL3MBTL1TSHR | |
| SCHEMBL1852629 | 0.68 | PPARD (0.43) | PPARDHMGCRPOLBTSHRCYP3A4 | |
| SCHEMBL17635917 | 0.67 | PPARD (0.41) | PPARDTSHRTP53TDP1LPAR3 | |
| SCHEMBL1732325 | 0.67 | PPARD (0.57) | PPARDTSHRTP53TDP1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0688325-A1 | PHOSPHONIC ACID DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020508-A1 | PHOSPHONIC ACID DERIVATIVES | EISAI CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |