Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617347 | 0.78 | PPARD (0.36) | ALDH1A1LMNAHMGCRCYP3A4CYP2C9 | |
| SCHEMBL21224619 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL22654331 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL74779 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10CYP3A4TSHR | |
| SCHEMBL221749 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10CYP3A4TSHR | |
| SCHEMBL271027 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10CYP3A4TSHR | |
| SCHEMBL11791908 | 0.71 | PTPN1 (0.41) | ALDH1A1LMNAHSD17B10CYP3A4TSHR | |
| SCHEMBL11791904 | 0.71 | PTPN1 (0.41) | ALDH1A1LMNAHSD17B10CYP3A4TSHR | |
| SCHEMBL17880417 | 0.71 | PTPN1 (0.41) | ALDH1A1LMNAHSD17B10CYP3A4TSHR | |
| SCHEMBL31298510 | 0.70 | PTPN1 (0.38) | ALDH1A1LMNAHSD17B10TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0688325-A1 | PHOSPHONIC ACID DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020508-A1 | PHOSPHONIC ACID DERIVATIVES | EISAI CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |