Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | TTPA | P49638 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039151 | 0.91 | PSEN1 (0.42) | ALOX5MEN1KMT2A | |
| SCHEMBL8616733 | 0.86 | ALOX5 (0.51) | ALOX5NR1I2MAPTLMNAMEN1 | |
| SCHEMBL8767474 | 0.78 | ALOX5 (0.51) | ALOX5NR1I2MAPTLMNAMEN1 | |
| SCHEMBL8767480 | 0.78 | ALOX5 (0.51) | ALOX5NR1I2MAPTLMNAMEN1 | |
| SCHEMBL9467277 | 0.77 | ALOX5 (0.60) | ALOX5NR1I2MAPTLMNAMEN1 | |
| SCHEMBL8618675 | 0.75 | PPARA (0.42) | ALOX5MAPTMEN1KMT2ATTPA | |
| SCHEMBL8768724 | 0.75 | ALOX5 (0.49) | ALOX5NR1I2MAPTLMNAMEN1 | |
| SCHEMBL9467233 | 0.72 | ALOX5 (0.55) | ALOX5NR1I2MAPTLMNAMEN1 | |
| SCHEMBL8923418 | 0.72 | ALOX5 (0.47) | ALOX5NR1I2MAPTLMNAMEN1 | |
| SCHEMBL8923422 | 0.72 | ALOX5 (0.47) | ALOX5NR1I2MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5734077-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, TREATMENT OF DIABETES AND ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 1998-03-31 | — | — | US | disclosed |