Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TTPA | P49638 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049826 | 0.88 | PSEN1 (0.41) | PPARA | |
| SCHEMBL8616733 | 0.82 | ALOX5 (0.51) | PPARAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8924155 | 0.78 | PPARA (0.42) | PPARAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8924165 | 0.78 | PPARA (0.42) | PPARAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8767383 | 0.76 | PTGS1 (0.43) | PPARAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8767394 | 0.76 | PTGS1 (0.43) | PPARAPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8617484 | 0.75 | ALOX5 (0.47) | TTPAMEN1MAPTKMT2ATDP1 | |
| SCHEMBL13086566 | 0.71 | PTGS1 (0.45) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL13086272 | 0.68 | MAPT (0.42) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9851129 | 0.67 | MAPT (0.50) | PTGS1PTGS2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5734077-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, TREATMENT OF DIABETES AND ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 1998-03-31 | — | — | US | disclosed |