Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 8/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617484 | 0.91 | ALOX5 (0.47) | ALOX5MEN1KMT2A | |
| SCHEMBL8616733 | 0.77 | ALOX5 (0.51) | ALOX5MEN1KMT2APPARA | |
| SCHEMBL8925726 | 0.74 | PSEN1 (0.44) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL8925722 | 0.74 | PSEN1 (0.44) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL8049826 | 0.71 | PSEN1 (0.41) | PSEN1PPARA | |
| SCHEMBL13084640 | 0.68 | PSEN1 (0.55) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL8767480 | 0.68 | ALOX5 (0.51) | ALOX5MEN1KMT2APPARA | |
| SCHEMBL8767474 | 0.68 | ALOX5 (0.51) | ALOX5MEN1KMT2APPARA | |
| SCHEMBL11705307 | 0.67 | PSEN1 (0.47) | PSEN1ALOX5MEN1KMT2APDE4A | |
| SCHEMBL9467277 | 0.67 | ALOX5 (0.60) | ALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763527-B1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-04-26 | — | — | EP | disclosed |
| EP-0763527-A1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-03-19 | — | — | EP | disclosed |