Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 6/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619769 | 0.87 | CDK2 (0.36) | CDK2CA2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8622828 | 0.84 | CDK2 (0.38) | CDK2CA2AURKAAURKBKDM4E | |
| SCHEMBL8623611 | 0.84 | CDK2 (0.38) | CDK2CA2KDM4EMEN1USP2 | |
| SCHEMBL8617963 | 0.81 | MAPT (0.39) | CA2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8619789 | 0.81 | CDK2 (0.35) | CDK2CA2KDM4EMEN1USP2 | |
| SCHEMBL8623637 | 0.79 | MAPT (0.40) | CA2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL8617656 | 0.78 | CDK2 (0.38) | CDK2CA2KDM4ELMNAMAPK1 | |
| SCHEMBL8616429 | 0.74 | MAPT (0.42) | KDM4EMEN1ALDH1A1LMNAMAPK1 | |
| SCHEMBL9037282 | 0.74 | CA2 (0.34) | CDK2CA2CA1CA9 | |
| SCHEMBL8622818 | 0.73 | CA2 (0.38) | CDK2CA2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |