Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623637 | 0.88 | MAPT (0.40) | MAPTKMT2APKMKDM4EHPGD | |
| SCHEMBL8617666 | 0.87 | CDK2 (0.39) | CDK2KMT2AKDM4ECYP1A2CA2 | |
| SCHEMBL8617963 | 0.86 | MAPT (0.39) | MAPTKMT2APKMKDM4EHPGD | |
| SCHEMBL8617977 | 0.85 | CDK2 (0.34) | CDK2MAPTKMT2APKMKDM4E | |
| SCHEMBL8623647 | 0.85 | CDK2 (0.34) | CDK2MAPTKMT2APKMKDM4E | |
| SCHEMBL8623629 | 0.82 | CA12 (0.36) | CDK2MAPTKMT2APKMKDM4E | |
| SCHEMBL8619763 | 0.81 | CA2 (0.40) | CDK2MAPTKMT2APKMKDM4E | |
| SCHEMBL8616429 | 0.81 | MAPT (0.42) | MAPTKMT2AKDM4EHPGDCYP1A2 | |
| SCHEMBL8621708 | 0.80 | MAPT (0.50) | MAPTKMT2AKDM4EHPGDCYP1A2 | |
| SCHEMBL9037445 | 0.78 | CA12 (0.42) | MAPTKMT2APKMKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |