Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620865 | 0.98 | TACR3 (0.46) | TACR3MEN1KMT2AATMDHODH | |
| SCHEMBL8617742 | 0.83 | TACR3 (0.63) | TACR3MEN1KMT2ADHODHKDM4E | |
| SCHEMBL8612632 | 0.83 | MEN1 (0.46) | TACR3MEN1KMT2ADHODHKDM4E | |
| SCHEMBL8613389 | 0.81 | DHODH (0.47) | TACR3MEN1KMT2ADHODHKDM4E | |
| SCHEMBL8613377 | 0.81 | TACR3 (0.48) | TACR3MEN1KMT2AATMKDM4E | |
| SCHEMBL8618730 | 0.81 | SMN1; SMN2 (0.56) | TACR3MEN1KMT2AATMKDM4E | |
| SCHEMBL8615050 | 0.81 | KMT2A (0.66) | TACR3MEN1KMT2AATMKDM4E | |
| SCHEMBL8614070 | 0.81 | CA2 (0.50) | TACR3MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8619731 | 0.81 | MEN1 (0.41) | TACR3MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8617827 | 0.80 | ALDH1A1 (0.51) | TACR3MEN1KMT2ADHODHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |