Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28783807 | 0.85 | HCAR3 (0.48) | ALDH1A1SIGMAR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1694355 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL8165221 | 0.80 | TP53 (0.47) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9543595 | 0.78 | KDM4E (0.50) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL4737907 | 0.76 | MAPT (0.44) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL4737915 | 0.76 | MAPT (0.44) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL13729336 | 0.72 | KDM4E (0.48) | ALDH1A1KDM4EKMT2AMEN1AR | |
| SCHEMBL13729340 | 0.72 | KDM4E (0.48) | ALDH1A1KDM4EKMT2AMEN1AR | |
| SCHEMBL601391 | 0.72 | ATM (0.46) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL169340 | 0.72 | MAPT (0.44) | ALDH1A1TSHRKMT2AMEN1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641764-B1 | Process for the preparation of hydroxyalkylaminonitrobenzene derivatives | CLARIANT GMBH (DE) | 1998-05-20 | — | — | EP | disclosed |
| EP-0641764-A2 | Process for the preparation of hydroxyalkylaminonitrobenzene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-08 | — | — | EP | disclosed |