Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618110 | 1.00 | TBXAS1 (0.44) | TBXAS1NPC1RAB9AHTR7CES2 | |
| SCHEMBL3361176 | 0.84 | KMT2A (0.55) | TBXAS1NPC1RAB9ACES2CES1 | |
| SCHEMBL3361173 | 0.84 | KMT2A (0.55) | TBXAS1NPC1RAB9ACES2CES1 | |
| SCHEMBL3361178 | 0.84 | KMT2A (0.55) | TBXAS1NPC1RAB9ACES2CES1 | |
| SCHEMBL28365872 | 0.82 | CES2 (0.43) | NPC1RAB9AHTR7CES2CES1 | |
| SCHEMBL10470024 | 0.82 | TBXAS1 (0.58) | TBXAS1NPC1RAB9ACES2CES1 | |
| SCHEMBL18691938 | 0.78 | TBXAS1 (0.42) | TBXAS1NPC1RAB9AHTR7CES2 | |
| SCHEMBL18691936 | 0.78 | TBXAS1 (0.42) | TBXAS1NPC1RAB9AHTR7CES2 | |
| SCHEMBL5636230 | 0.77 | ALOX5 (0.41) | NPC1RAB9AHTR7CES2CES1 | |
| SCHEMBL5636232 | 0.77 | ALOX5 (0.41) | NPC1RAB9AHTR7CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0688325-A1 | PHOSPHONIC ACID DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020508-A1 | PHOSPHONIC ACID DERIVATIVES | EISAI CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |