Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622051 | 0.90 | ANO1 (0.50) | MRGPRX4ADRB2PTGDR2MAPT | |
| SCHEMBL8617384 | 0.90 | MRGPRX4 (0.45) | MRGPRX4ADRB2PTGDR2MAPT | |
| SCHEMBL8619242 | 0.86 | HDAC8 (0.41) | MRGPRX4PTGDR2MAPT | |
| SCHEMBL8620420 | 0.82 | HIF1A (0.44) | MRGPRX4MAPT | |
| SCHEMBL8622457 | 0.82 | L3MBTL1 (0.40) | PTGDR2MAPT | |
| SCHEMBL8620577 | 0.82 | PARP10 (0.47) | MAPT | |
| SCHEMBL8617222 | 0.81 | CDK4 (0.44) | PTGDR2MAPT | |
| SCHEMBL8620478 | 0.81 | MRGPRX4 (0.43) | MRGPRX4PTGDR2MAPT | |
| SCHEMBL8617286 | 0.81 | PTGDR2 (0.46) | PTGDR2MAPT | |
| SCHEMBL8617305 | 0.81 | ALDH1A1 (0.52) | MRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |