Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618530 | 1.00 | ALDH1A1 (0.48) | ALDH1A1GAASMN1; SMN2HPGDPOLB | |
| SCHEMBL8059143 | 0.77 | HSP90AA1 (0.46) | ALDH1A1GAASMN1; SMN2HPGDPOLB | |
| SCHEMBL7531104 | 0.76 | HSP90AA1 (0.49) | GAASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL16272178 | 0.76 | HSP90AA1 (0.45) | ALDH1A1GAASMN1; SMN2HPGDPOLB | |
| SCHEMBL19424019 | 0.76 | HSP90AA1 (0.45) | ALDH1A1GAASMN1; SMN2HPGDPOLB | |
| SCHEMBL18386576 | 0.76 | HSP90AA1 (0.45) | ALDH1A1GAASMN1; SMN2HPGDPOLB | |
| SCHEMBL18059140 | 0.76 | HSP90AA1 (0.45) | ALDH1A1GAASMN1; SMN2HPGDPOLB | |
| SCHEMBL20726184 | 0.76 | HSP90AA1 (0.45) | ALDH1A1GAASMN1; SMN2HPGDPOLB | |
| SCHEMBL21139383 | 0.76 | HSP90AA1 (0.45) | ALDH1A1GAASMN1; SMN2HPGDPOLB | |
| SCHEMBL10534961 | 0.76 | HSP90AA1 (0.45) | ALDH1A1GAASMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716948-A | 3-substituted carbacephems | PFIZER INC. (US) | 1998-02-10 | — | — | US | disclosed |
| WO-1993025551-A1 | 3-SUBSTITUTED CARBACEPHEMS | SMITHKLINE BEECHAM PLC (GB) | 1993-12-23 | — | — | WO | disclosed |