Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617305 | 0.86 | ALDH1A1 (0.52) | PARP10PARP14HIF1AMAOBMAOA | |
| SCHEMBL8621226 | 0.83 | L3MBTL1 (0.46) | PARP10PARP14HIF1AMAOBMAPT | |
| SCHEMBL8623908 | 0.82 | HIF1A (0.46) | PARP10PARP14HIF1AMAOBMAOA | |
| SCHEMBL8618547 | 0.82 | MRGPRX4 (0.54) | MAPT | |
| SCHEMBL8621428 | 0.81 | MAPT (0.45) | PARP10PARP14HIF1AMAOBMAOA | |
| SCHEMBL8621319 | 0.81 | HIF1A (0.48) | PARP10PARP14HIF1AMAOBMAPT | |
| SCHEMBL8620428 | 0.80 | HIF1A (0.42) | PARP10PARP14HIF1AMAOBMAPT | |
| SCHEMBL8622766 | 0.79 | HIF1A (0.52) | HIF1AMAOBMAPTL3MBTL1 | |
| SCHEMBL8617384 | 0.79 | MRGPRX4 (0.45) | MAPTNPC1L3MBTL1 | |
| SCHEMBL8622051 | 0.79 | ANO1 (0.50) | HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |