Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628279 | 0.79 | CYP3A4 (0.40) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL8117201 | 0.77 | BRD4 (0.42) | NOTUMALDH1A1GAAKDM4ETSHR | |
| SCHEMBL11797429 | 0.74 | TSHR (0.38) | ALDH1A1GAAKDM4EMAPTTSHR | |
| SCHEMBL10623715 | 0.74 | CYP3A4 (0.50) | ALDH1A1KMT2AGAAKDM4EMAPT | |
| SCHEMBL8620821 | 0.74 | — | — | |
| SCHEMBL10609471 | 0.67 | — | — | |
| SCHEMBL10628315 | 0.66 | MAOA (0.44) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL28215 | 0.61 | CYP1A2 (0.73) | NOTUMALDH1A1CYP1A2TSHRLMNA | |
| SCHEMBL3952742 | 0.61 | CYP1A2 (0.73) | NOTUMALDH1A1CYP1A2TSHRLMNA | |
| SCHEMBL11165087 | 0.61 | CYP1A2 (0.73) | NOTUMALDH1A1CYP1A2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849861-A | Polyquinazolines and methods for their preparation | HITACHI CHEMICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| US-5686560-A | TREATING A MONOMER WITH A BASE IN A DIPOLAR SOLVENT | HITACHI CHEMICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |