Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 13/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 12/20 | 1.00 |
| ▸ | GUSB | P08236 | 8/20 | 1.00 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 1.00 |
| ▸ | PARP1 | P09874 | 6/20 | 0.78 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | WNT3A | P56704 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885282 | 0.92 | TNKS (0.93) | TNKSTNKS2GUSBPARP2PARP1 | |
| SCHEMBL6124189 | 0.88 | TNKS (0.93) | TNKSTNKS2GUSBPARP2PARP1 | |
| SCHEMBL29592833 | 0.88 | TNKS (1.00) | TNKSTNKS2GUSBPARP2PARP1 | |
| SCHEMBL258433 | 0.88 | TNKS (1.00) | TNKSTNKS2GUSBPARP2PARP1 | |
| Hydrochloric Acid SCHEMBL31529601 | 0.86 | TNKS (0.96) | TNKSTNKS2GUSBPARP2PARP1 | |
| SCHEMBL400070 | 0.84 | TNKS (0.73) | TNKSTNKS2GUSBPARP2PARP1 | |
| SCHEMBL29764046 | 0.84 | TNKS (0.73) | TNKSTNKS2GUSBPARP2PARP1 | |
| SCHEMBL15775207 | 0.84 | TNKS (1.00) | TNKSTNKS2GUSBPARP2PARP1 | |
| SCHEMBL8618982 | 0.84 | TNKS (1.00) | TNKSTNKS2GUSBPARP2PARP1 | |
| SCHEMBL7765127 | 0.84 | TNKS (1.00) | TNKSTNKS2GUSBPARP2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116159594-B | Application of pyridinium small molecule as photocatalyst in alcohol and amine series reaction | 北京理工大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-115650924-B | Green synthesis method of quinazolinone | 山东华泰新材料技术研发有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-118359548-A | Preparation method of benzodiazepine compound | 重庆医科大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-117964560-A | Method for constructing quinazolinone derivative through oxidization | 淮阴工学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-114591251-B | Chiral aminoquinazoline compound, and preparation method and application thereof | 华南理工大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-116159594-A | Application of pyridinium small molecule as photocatalyst in alcohol and amine series reaction | 北京理工大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-115650924-A | Green synthesis method of quinazolinone | 上海橡实化学有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-112645887-B | Preparation method of quinazolinone derivative | 淮阴工学院（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-113185468-B | Method for synthesizing quinazolinone through photocatalysis | 上海橡实化学有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-109879820-B | Synthetic method of quinazolinone heterocyclic compound | 扬州大学 | 2022-07-19 | — | — | CN | disclosed |
| US-20140256754-A1 | QUINAZOLINES AS B-GLUCURONIDASE NOVEL INHIBITORS | CHOUDHARY MUHAMMAD IQBAL (PK) | 2014-09-11 | — | — | US | disclosed |
| US-20140256754-A1 | QUINAZOLINES AS B-GLUCURONIDASE NOVEL INHIBITORS | CHOUDHARY MUHAMMAD IQBAL (PK) | 2014-09-11 | — | — | US | disclosed |
| US-20140256754-A1 | QUINAZOLINES AS B-GLUCURONIDASE NOVEL INHIBITORS | CHOUDHARY MUHAMMAD IQBAL (PK) | 2014-09-11 | — | — | US | disclosed |
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |
| CN-103408502-A | Synthetic method of quinazolinone compounds | UNIV HUNAN | 2013-11-27 | — | — | CN | disclosed |
| US-5849861-A | Polyquinazolines and methods for their preparation | HITACHI CHEMICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| US-5686560-A | TREATING A MONOMER WITH A BASE IN A DIPOLAR SOLVENT | HITACHI CHEMICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| US-4431440-A | 2-/4-METHYLPHENYL/-4-3H-QUINAZOLINES AS HERBICIDES AND PLANT GROWTH REGULATORS; CEREALS | AMERICAN CYANAMID COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0058822-A1 | Method to alter or control the development and/or life cycle of various plant species | AMERICAN CYANAMID COMPANY (US) | 1982-09-01 | — | — | EP | disclosed |
| US-3998951-A | Substituted 2-arylquinazolines as fungicides | FMC CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256754-A1 | QUINAZOLINES AS B-GLUCURONIDASE NOVEL INHIBITORS | GUSB, GBA3, GAA | TNKS 1726/4885TNKS2 1674/4885GUSB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.