Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL129722 | 0.82 | TSHR (0.53) | TSHRALDH1A1 | |
| Tetrahydrofuran SCHEMBL9067165 | 0.82 | ALDH1A1 (0.47) | ALDH1A1 | |
| Dimethylformamide SCHEMBL2184966 | 0.82 | TSHR (0.53) | TSHR | |
| Dimethylformamide SCHEMBL124684 | 0.82 | TSHR (0.53) | TSHR | |
| Tetrahydrofuran SCHEMBL6171686 | 0.82 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL3423848 | 0.80 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL28247936 | 0.80 | ALDH1A1 (0.44) | ALDH1A1 | |
| Tetrahydrofuran SCHEMBL28743802 | 0.80 | TSHR (0.50) | TSHRALDH1A1 | |
| Dimethylformamide SCHEMBL1072443 | 0.80 | TSHR (0.50) | TSHRALDH1A1 | |
| Tetrahydrofuran SCHEMBL2439396 | 0.78 | TSHR (0.47) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052913-A2 | LEUKOTRIENE B4 ANTAGONISTS, IN PARTICULAR 3-OXA-TETRAHYDRONAPHTHALENE-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |