Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.40 |
| ▸ | HTR3A | P46098 | 3/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794711 | 0.83 | KDM2B (0.48) | KDM2BFAAHHRH4L3MBTL1CHRNA7 | |
| SCHEMBL8619492 | 0.80 | ALDH1A1 (0.50) | POLB | |
| SCHEMBL8621416 | 0.78 | CYP3A4 (0.47) | L3MBTL1CHRNA7POLB | |
| SCHEMBL23079084 | 0.77 | BCL2L1 (0.61) | KDM2BHRH4L3MBTL1CHRNA7HTR3A | |
| SCHEMBL31264285 | 0.75 | KDM2B (0.56) | KDM2BFAAHHRH4L3MBTL1CHRNA7 | |
| SCHEMBL4674322 | 0.73 | KDM2B (0.53) | KDM2BHRH4L3MBTL1CHRNA7HTR3A | |
| SCHEMBL4674326 | 0.72 | BCL2L1 (0.54) | KDM2BHRH4L3MBTL1CHRNA7HTR3A | |
| SCHEMBL7840921 | 0.70 | HTR2A (0.62) | KDM2BFAAHHRH3 | |
| SCHEMBL8617445 | 0.69 | GPR119 (0.44) | L3MBTL1HRH3POLB | |
| SCHEMBL5505440 | 0.67 | KDM2B (0.67) | KDM2BHRH4L3MBTL1CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |