SCHEMBL8619086

SCHEMBL8619086

CCC/C=C/c1ccc(C#Cc2ccc(CCC)c(F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 18/20 0.43
FFAR4 Q5NUL3 15/20 0.43
TSPO P30536 1/20 0.36
DRD3 P35462 1/20 0.36
GSK3B P49841 1/20 0.32
BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8619094 1.00 FFAR1 (0.43) FFAR1FFAR4TSPODRD3GSK3B
SCHEMBL8617834 0.86 NFE2L2 (0.40) FFAR1FFAR4
SCHEMBL8617838 0.86 NFE2L2 (0.40) FFAR1FFAR4
SCHEMBL7859840 0.84 FFAR1 (0.55) FFAR1FFAR4TSPODRD3
SCHEMBL8621471 0.83 FFAR1 (0.34) FFAR1FFAR4
SCHEMBL8621475 0.83 FFAR1 (0.34) FFAR1FFAR4
SCHEMBL8622908 0.81 FFAR1 (0.43) FFAR1
SCHEMBL8622912 0.81 FFAR1 (0.43) FFAR1
SCHEMBL8616906 0.80 TRPV4 (0.36) FFAR1FFAR4TSPODRD3
SCHEMBL8616904 0.80 TRPV4 (0.36) FFAR1FFAR4TSPODRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648723-B1 Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-05-20 EP disclosed
US-5658489-A EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-19 US disclosed
EP-0648723-A1 Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed