SCHEMBL86191

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11873711	0.88	ELANE (0.51)	ELANEAKR1B1ALDH1A1SMN1; SMN2ACHE
	SCHEMBL86279	0.81	ACHE (0.59)	AKR1B1ALDH1A1SMN1; SMN2ACHEMAPK14
	SCHEMBL31510701	0.81	ACHE (0.59)	AKR1B1ALDH1A1SMN1; SMN2ACHEMAPK14
	SCHEMBL31123671	0.81	ACHE (0.59)	AKR1B1ALDH1A1SMN1; SMN2ACHEMAPK14
	SCHEMBL13871237	0.81	NPC1 (0.51)	AKR1B1ALDH1A1SMN1; SMN2ACHEMAPK14
	SCHEMBL86282	0.81	AKR1B1 (0.46)	AKR1B1ACHEMAPK14MAPTNOTUM
	SCHEMBL86749	0.81	MAOB (0.54)	AKR1B1ACHEMAPK14MEN1KMT2A
	SCHEMBL86333	0.81	AKR1B1 (0.46)	AKR1B1ALDH1A1SMN1; SMN2ACHEMAPK14
	SCHEMBL86330	0.81	TDP1 (0.59)	AKR1B1METAP1ACHEMAPK14MAPT
	SCHEMBL86298	0.81	MMP12 (0.47)	METAP1SMN1; SMN2MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.