Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31510701 | 1.00 | ACHE (0.59) | ACHEAKR1B1MAOAMAPK14CES1 | |
| SCHEMBL86279 | 1.00 | ACHE (0.59) | ACHEAKR1B1MAOAMAPK14CES1 | |
| SCHEMBL216973 | 0.83 | ACHE (0.56) | ACHEAKR1B1ALDH1A1CHRM2ADRA2A | |
| SCHEMBL4231216 | 0.81 | MAPK14 (0.62) | ACHEAKR1B1MAOAMAPK14CES1 | |
| SCHEMBL85994 | 0.81 | AKR1B1 (0.49) | ACHEAKR1B1MAOAMAPK14CES1 | |
| SCHEMBL7243476 | 0.81 | ALDH1A1 (0.54) | ACHEAKR1B1MAOAMAPK14MIF | |
| SCHEMBL9044156 | 0.81 | TDP1 (0.59) | ACHEAKR1B1MAOAMAPK14CES1 | |
| SCHEMBL13871237 | 0.81 | NPC1 (0.51) | ACHEAKR1B1MAPK14MIFMAOB | |
| SCHEMBL91640 | 0.81 | VHL (0.51) | ACHEAKR1B1MAOAMAPK14MAOB | |
| SCHEMBL13870605 | 0.81 | AKR1B1 (0.49) | ACHEAKR1B1MAOAMAPK14MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074907-A1 | INHIBITORS OF SARS-COV-2 | THE TEXAS A&M UNIVERSITY SYSTEM | 2025-03-06 | — | — | US | disclosed |
| WO-2024205377-A1 | NOVEL COMPOUNDS WITH MTORC2-INHIBITORY ACTIVITY AND USES THEREOF | 알리아드바이오파마 주식회사 | 2024-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074907-A1 | INHIBITORS OF SARS-COV-2 | ACE2, ACE, SARS1 | ACHE 1938/4885AKR1B1 4317/4885MAOA 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.