Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8620197 | 0.99 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AHDAC1SMN1; SMN2 | |
| SCHEMBL8615748 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL8614253 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8966793 | 0.86 | HDAC1 (0.37) | ALDH1A1MAPTKMT2AHDAC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8966715 | 0.85 | L3MBTL1 (0.38) | ALDH1A1MAPTKMT2AHDAC1SMN1; SMN2 | |
| SCHEMBL8616106 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AHDAC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8617887 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AHDAC1SMN1; SMN2 | |
| SCHEMBL8614877 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8614975 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2AHDAC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8615124 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AHDAC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |