Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303817 | 0.78 | KDM4E (0.40) | KDM4EKMT2AMEN1ALDH1A1ITGB3 | |
| SCHEMBL8619238 | 0.77 | KDM4E (0.35) | KDM4EKMT2AMEN1ALDH1A1ITGB3 | |
| SCHEMBL8301327 | 0.72 | KDM4E (0.43) | KDM4EKMT2AMEN1ALDH1A1ITGB3 | |
| SCHEMBL8613430 | 0.67 | KDM4E (0.50) | KDM4EKMT2AMEN1ALDH1A1HRH3 | |
| SCHEMBL13860480 | 0.65 | MAPT (0.45) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL8615320 | 0.63 | KDM2B (0.34) | KDM4EKMT2AMEN1ALDH1A1ITGB3 | |
| SCHEMBL8300676 | 0.63 | KDM4E (0.42) | KDM4EKMT2AMEN1ALDH1A1ITGB3 | |
| SCHEMBL8300631 | 0.63 | GRIN2B (0.40) | KDM4EKMT2AMEN1ALDH1A1ITGB3 | |
| SCHEMBL1196914 | 0.62 | NOS2 (0.65) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL8301361 | 0.61 | CYP2D6 (0.39) | KDM4EKMT2AMEN1ALDH1A1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |