Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303817 | 0.80 | KDM4E (0.40) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8300631 | 0.74 | GRIN2B (0.40) | KDM4EMEN1ALDH1A1KMT2ACCR2 | |
| SCHEMBL8301361 | 0.73 | CYP2D6 (0.39) | KDM4EMEN1ALDH1A1KMT2ACCR2 | |
| SCHEMBL8300676 | 0.72 | KDM4E (0.42) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8299936 | 0.71 | KDM4E (0.41) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8301126 | 0.70 | KDM4E (0.40) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8300200 | 0.70 | KDM4E (0.37) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL7399382 | 0.69 | ITGB3 (0.49) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL7399380 | 0.69 | ITGB3 (0.49) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8301158 | 0.66 | CCR2 (0.35) | CCR2HTR2AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |