Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621371 | 0.89 | CRHR1 (0.67) | CRHR1TDP1 | |
| SCHEMBL8617375 | 0.88 | CRHR1 (1.00) | CRHR1TDP1 | |
| SCHEMBL7215931 | 0.80 | CRHR1 (0.57) | CRHR1TDP1 | |
| SCHEMBL7217519 | 0.80 | CRHR1 (0.53) | CRHR1TDP1 | |
| SCHEMBL7217860 | 0.72 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL7222478 | 0.72 | CRHR1 (0.55) | CRHR1 | |
| Antalarmin SCHEMBL29832078 | 0.71 | CRHR1 (1.00) | CRHR1TDP1 | |
| Antalarmin SCHEMBL466243 | 0.71 | CRHR1 (1.00) | CRHR1TDP1 | |
| SCHEMBL6295712 | 0.71 | CRHR1 (0.59) | CRHR1 | |
| Antalarmin SCHEMBL25395568 | 0.71 | CRHR1 (0.98) | CRHR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998045295-A1 | CERTAIN PYRROLOPYRIDINE DERIVATIVES; NOVEL CRF1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1998-10-15 | — | — | WO | disclosed |