Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616294 | 1.00 | SIGMAR1 (0.47) | SIGMAR1CHRM2ALDH1A1ALOX12KMT2A | |
| SCHEMBL8613522 | 0.97 | SIGMAR1 (0.47) | SIGMAR1CHRM2ALDH1A1ALOX12KMT2A | |
| SCHEMBL8613527 | 0.97 | SIGMAR1 (0.47) | SIGMAR1CHRM2ALDH1A1ALOX12KMT2A | |
| SCHEMBL15271423 | 0.91 | ALDH1A1 (0.51) | ALDH1A1ALOX12KMT2AMAPTNPC1 | |
| SCHEMBL15270700 | 0.91 | ALDH1A1 (0.51) | ALDH1A1ALOX12KMT2AMAPTNPC1 | |
| SCHEMBL15271663 | 0.91 | ALDH1A1 (0.51) | ALDH1A1ALOX12KMT2AMAPTNPC1 | |
| SCHEMBL15270973 | 0.91 | ALDH1A1 (0.51) | ALDH1A1ALOX12KMT2AMAPTNPC1 | |
| SCHEMBL11728517 | 0.91 | ALDH1A1 (0.51) | ALDH1A1ALOX12KMT2AMAPTNPC1 | |
| SCHEMBL10723137 | 0.91 | ALDH1A1 (0.51) | ALDH1A1ALOX12KMT2AMAPTNPC1 | |
| SCHEMBL27959557 | 0.91 | ALDH1A1 (0.51) | ALDH1A1ALOX12KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |