Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281947 | 0.79 | MAPT (0.50) | MEN1KMT2AMAPTNPSR1TSHR | |
| SCHEMBL5156820 | 0.78 | ITGB1 (0.58) | MEN1KMT2AMAPTNPSR1TSHR | |
| SCHEMBL8619632 | 0.77 | CYP1A2 (0.38) | ALDH1A1KDM4ELMNACYP1A2POLB | |
| SCHEMBL5151715 | 0.76 | MEN1 (0.54) | MEN1KMT2AMAPTNPSR1TSHR | |
| SCHEMBL6166911 | 0.74 | MAPT (0.58) | MEN1KMT2AMAPTNPSR1TSHR | |
| SCHEMBL6597529 | 0.73 | MEN1 (0.56) | MEN1KMT2AMAPTNPSR1TSHR | |
| SCHEMBL6881329 | 0.73 | CA2 (0.38) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL8868300 | 0.73 | ALDH1A1 (0.59) | MEN1KMT2AMAPTNPSR1TSHR | |
| SCHEMBL8868308 | 0.73 | MAPT (0.55) | MEN1KMT2AMAPTNPSR1TSHR | |
| SCHEMBL5271137 | 0.72 | RAB9A (0.58) | MEN1KMT2AMAPTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842196-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1998-05-20 | — | — | EP | disclosed |