Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861969 | 1.00 | ATG4B (0.50) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL861971 | 1.00 | ATG4B (0.50) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL27550293 | 0.79 | LMNA (0.51) | CYP1A2TDP1RECQL | |
| SCHEMBL5477920 | 0.76 | HCAR2 (0.58) | ATG4BPLA2G1B | |
| SCHEMBL14680403 | 0.74 | TP53 (0.65) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL729878 | 0.74 | HCAR2 (0.59) | TDP1TSHR | |
| SCHEMBL14415089 | 0.74 | HCAR2 (0.59) | TDP1TSHR | |
| SCHEMBL10670938 | 0.74 | HCAR2 (0.59) | TDP1TSHR | |
| SCHEMBL28349553 | 0.73 | HCAR2 (0.44) | THRATHRBTSHR | |
| SCHEMBL28432501 | 0.72 | TP53 (0.61) | THRATHRBABCG2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143465-B2 | Soluble branched triaroylbenzene-based polymer and its synthetic method | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2012-03-27 | — | — | US | disclosed |
| US-20060247410-A1 | Soluble branched triaroylbenzene-based polymer and its synthetic method | HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) | 2006-11-02 | — | — | US | disclosed |