Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | AKT1 | P31749 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.46 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.46 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10275631 | 0.86 | AKT1 (0.54) | LMNAAKT1MAPTRAB9ANPC1 | |
| SCHEMBL10439177 | 0.86 | AKT1 (0.54) | LMNAAKT1MAPTRAB9ANPC1 | |
| SCHEMBL10275628 | 0.86 | AKT1 (0.54) | LMNAAKT1MAPTRAB9ANPC1 | |
| SCHEMBL27342596 | 0.82 | LMNA (0.55) | LMNAAKT1MAPTRAB9ANPC1 | |
| SCHEMBL861969 | 0.79 | ATG4B (0.50) | RECQLCYP1A2TDP1 | |
| SCHEMBL861970 | 0.79 | ATG4B (0.50) | RECQLCYP1A2TDP1 | |
| SCHEMBL861971 | 0.79 | ATG4B (0.50) | RECQLCYP1A2TDP1 | |
| SCHEMBL12587226 | 0.78 | MAOB (0.52) | LMNAMAPTRAB9ANPC1KMT2A | |
| SCHEMBL9751081 | 0.78 | LMNA (0.59) | LMNAAKT1MAPTRAB9ANPC1 | |
| SCHEMBL12587160 | 0.77 | BCHE (0.57) | LMNAMAPTRAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1274655-C | Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same | SERVIER LAB (FR) | 2006-09-13 | — | — | CN | disclosed |
| CN-1628088-A | Novel 3-aryl-2, 5-dihydroxy-1, 4-benzoquinones, process for preparing same and pharmaceutical compositions containing same | SERVIER LAB (FR) | 2005-06-15 | — | — | CN | disclosed |