Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619652 | 0.88 | MEN1 (0.49) | KMT2AMAPTMEN1TDP1PPARG | |
| SCHEMBL8615053 | 0.86 | PPARG (0.52) | KMT2AMAPTMEN1TDP1PPARG | |
| SCHEMBL8620610 | 0.84 | PPARG (0.49) | KMT2AMAPTMEN1TDP1PPARG | |
| SCHEMBL8619591 | 0.82 | PPARG (0.50) | KMT2AMAPTMEN1TDP1PPARG | |
| SCHEMBL8619704 | 0.81 | MAPT (0.57) | KMT2AMAPTMEN1TDP1PPARG | |
| SCHEMBL8003203 | 0.80 | MAPT (0.64) | KMT2AMAPTMEN1TDP1PPARG | |
| SCHEMBL9265028 | 0.78 | PTGS1 (0.51) | KMT2AMAPTMEN1KDM4ECYP3A4 | |
| SCHEMBL7986932 | 0.77 | MAPT (0.61) | KMT2AMAPTMEN1TDP1PPARG | |
| SCHEMBL9312815 | 0.75 | PTGS1 (0.58) | KMT2AMAPTMEN1KDM4ECYP3A4 | |
| SCHEMBL7492850 | 0.75 | MAPT (0.59) | KMT2AMAPTMEN1TDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747528-A | Chroman derivatives as anti-oxidants | WARNER-LAMBERT COMPANY (US) | 1998-05-05 | — | — | US | claimed |