Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | PLG | P00747 | 4/20 | 0.35 |
| ▸ | PLAU | P00749 | 4/20 | 0.35 |
| ▸ | PLAT | P00750 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 3/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619913 | 0.86 | TGFBR1 (0.39) | MEN1POLBKMT2AACP1KDM4E | |
| SCHEMBL8618132 | 0.84 | DNMT1 (0.36) | MEN1POLBKMT2AACP1DNMT1 | |
| SCHEMBL8620877 | 0.84 | HTT (0.39) | MEN1POLBKMT2AACP1KDM4E | |
| SCHEMBL8615489 | 0.84 | KCNH2 (0.35) | MEN1POLBKMT2AACP1KDM4E | |
| SCHEMBL8615341 | 0.84 | MEN1 (0.39) | MEN1KMT2AABL1KDM4EALDH1A1 | |
| SCHEMBL8620868 | 0.83 | ACP1 (0.42) | PDE4BPDE4DPDE4APDE4CF10 | |
| SCHEMBL8617721 | 0.82 | CA2 (0.38) | MEN1POLBKMT2AACP1DNMT1 | |
| SCHEMBL8613232 | 0.82 | TACR3 (0.36) | MEN1POLBKMT2AACP1DNMT1 | |
| SCHEMBL8619973 | 0.82 | TACR3 (0.34) | MEN1POLBKMT2AACP1KDM4E | |
| SCHEMBL8618522 | 0.82 | ABL1 (0.36) | MEN1KMT2ADNMT1EHMT2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |