Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 8/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | PLG | P00747 | 4/20 | 0.37 |
| ▸ | PLAU | P00749 | 4/20 | 0.37 |
| ▸ | PLAT | P00750 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617804 | 0.98 | ACP1 (0.42) | ACP1PDE10AF10PLGPLAU | |
| SCHEMBL8617748 | 0.84 | ACP1 (0.52) | ACP1KDM4EMEN1KMT2ATACR3 | |
| SCHEMBL8613391 | 0.83 | ACP1 (0.40) | ACP1KDM4EMEN1KMT2A | |
| SCHEMBL8619735 | 0.83 | PDE4B (0.35) | ACP1F10PLGPLAUPLAT | |
| SCHEMBL8617830 | 0.82 | ACP1 (0.46) | ACP1PLGPLAUPLATF2 | |
| SCHEMBL8618733 | 0.81 | LMNA (0.45) | ACP1PDE10AKDM4EMEN1KMT2A | |
| SCHEMBL8615054 | 0.81 | PDE10A (0.55) | ACP1PDE10AKDM4EMEN1KMT2A | |
| SCHEMBL8613381 | 0.81 | ACP1 (0.46) | ACP1PDE10A | |
| SCHEMBL8612634 | 0.81 | ACP1 (0.40) | ACP1MEN1KMT2AATM | |
| SCHEMBL8617721 | 0.81 | CA2 (0.38) | ACP1KDM4EMEN1KMT2ATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |