SCHEMBL861977

SCHEMBL861977

Cc1cc(C(C)C)c(-c2cnc3c4ccccc4c4cc(C)ccc4n23)c(C(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.35
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
RORB Q92753 1/20 0.35
MEN1 O00255 1/20 0.33
NR1I2 O75469 1/20 0.33
AHR P35869 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861219 0.93 RORA (0.34) PGRRORARORCRORBMEN1
SCHEMBL840348 0.93 PGR (0.35) PGRRORARORCRORBMEN1
SCHEMBL861600 0.92 PGR (0.33) PGRRORARORCRORBMEN1
SCHEMBL12759654 0.85 PGR (0.38) PGRRORARORCRORBMEN1
SCHEMBL12759649 0.84 MEN1 (0.39) PGRRORARORCRORBMEN1
SCHEMBL29631725 0.83 PGR (0.38) PGRRORARORCRORBMEN1
SCHEMBL841646 0.83 PGR (0.38) PGRRORARORCRORBMEN1
SCHEMBL29801927 0.81 PGR (0.37) PGRRORARORCRORBMEN1
SCHEMBL29911566 0.81 PGR (0.37) PGRRORARORCRORBMEN1
SCHEMBL879022 0.81 RORA (0.32) RORARORCRORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C PGR 3621/4885RORA 2304/4885RORC 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.