SCHEMBL8619876

SCHEMBL8619876

Cn1nc(-c2cc(S(=O)(=O)Cl)c(Cl)cc2Cl)c(Cl)c1OC(F)F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9081659 0.91 TRPV4 (0.32) TRPV4
SCHEMBL8625222 0.87 L3MBTL1 (0.36) L3MBTL1
SCHEMBL7711793 0.82 TRPV4 (0.35) TRPV4
SCHEMBL7839306 0.81 L3MBTL1 (0.31) L3MBTL1
SCHEMBL6586163 0.80 SCN9A (0.32)
SCHEMBL9405155 0.80
SCHEMBL7841255 0.80
SCHEMBL8619976 0.79 PPOX (0.32)
SCHEMBL7829990 0.79 TSHR (0.34) L3MBTL1
SCHEMBL8183820 0.79 NTRK1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443059-B1 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO LTD (JP) 1998-06-17 EP disclosed
EP-0361114-B1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO LTD (JP) 1998-06-03 EP disclosed
EP-0443059-A1 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1991-08-28 EP disclosed
US-5032165-A 3-(substituted phenyl)pyrazole derivatives, salts thereof, and herbicides therefrom NIHON NOHYAKU COMPANY, LTD. (JP) 1991-07-16 US disclosed
EP-0361114-A1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1990-04-04 EP disclosed