Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 16/20 | 0.49 |
| ▸ | PGR | P06401 | 13/20 | 0.49 |
| ▸ | AR | P10275 | 11/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624310 | 0.88 | NR3C1 (0.62) | NR3C1PGRARCYP2C8CYP3A4 | |
| SCHEMBL8621595 | 0.85 | NR3C1 (0.60) | NR3C1PGRARCYP2C8CYP3A4 | |
| SCHEMBL8620743 | 0.81 | NR3C1 (0.45) | NR3C1PGRARCYP2C8CYP3A4 | |
| SCHEMBL8618683 | 0.79 | NR3C1 (0.50) | NR3C1PGRARCYP2C8CYP3A4 | |
| SCHEMBL9019846 | 0.74 | NR3C1 (0.83) | NR3C1PGRARCYP2C8CYP3A4 | |
| SCHEMBL8407056 | 0.73 | NR3C1 (0.48) | NR3C1PGRARCYP2C8CYP3A4 | |
| SCHEMBL8409143 | 0.72 | PGR (0.42) | NR3C1PGRARCYP2C8CYP3A4 | |
| SCHEMBL21729781 | 0.71 | NR3C1 (0.68) | NR3C1PGRARCYP2C8CYP3A4 | |
| SCHEMBL19042656 | 0.71 | NR3C1 (0.68) | NR3C1PGRARCYP2C8CYP3A4 | |
| SCHEMBL19042670 | 0.70 | NR3C1 (0.60) | NR3C1PGRARCYP2C8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |