Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 15/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 14/20 | 0.42 |
| ▸ | AR | P10275 | 11/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407122 | 0.79 | PGR (0.40) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL9019878 | 0.77 | NR3C1 (0.69) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL8624310 | 0.76 | NR3C1 (0.62) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL8621595 | 0.76 | NR3C1 (0.60) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL8767796 | 0.76 | PGR (0.55) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8410403 | 0.73 | NR3C1 (0.35) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL8536118 | 0.72 | PGR (0.51) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8536387 | 0.72 | PGR (0.51) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8619912 | 0.72 | NR3C1 (0.49) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL8618683 | 0.71 | NR3C1 (0.50) | PGRNR3C1ARCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |