Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328869 | 0.76 | CHRM2 (0.44) | CHRM2ACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL8325662 | 0.76 | CHRM2 (0.46) | CHRM2ACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL8329010 | 0.74 | CHRM2 (0.41) | CHRM2ACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL8324185 | 0.68 | CHRM2 (0.39) | CHRM2ACHESCN8ALMNATP53 | |
| SCHEMBL10045185 | 0.67 | CHRM2 (0.92) | CHRM2ACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL8330575 | 0.65 | MEN1 (0.35) | CHRM2ACHESCN8ALMNATP53 | |
| SCHEMBL10045186 | 0.65 | CHRM2 (0.88) | CHRM2ACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL12332531 | 0.64 | CHRM2 (0.66) | CHRM2ACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL8322051 | 0.64 | ALDH1A1 (0.42) | TP53L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL14619486 | 0.63 | CHRM2 (0.76) | CHRM2ACHEHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |